This HITEQ Center webinar explored key concepts and best practices that should be followed by Health Centers seeking to develop Defense in Depth and effectively implement hardened security programs at their sites. There are ever-increasing cybersecurity guidelines and protection measures that Health Centers must navigate and digest. This webinar sought to motivate and educate the health center workforce on critical privacy and security concepts and methods for defense. Aspects of Security Risk Assessment, security awareness training, and breach protection were covered with an emphasis on health center-wide information protection.